Single-dose treatment with a humanized neutralizing antibody affords full protection of a human transgenic mouse model from lethal Middle East respiratory syndrome (MERS)-coronavirus infection

Middle East respiratory syndrome coronavirus (MERS-CoV) is continuously spreading and causing severe and fatal acute respiratory disease in humans. Prophylactic and therapeutic strategies are therefore urgently needed to control MERS-CoV infection. Here, we generated a humanized monoclonal antibody...

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Detalles Bibliográficos
Autores principales: Qiu, Hongjie, Sun, Shihui, Xiao, He, Feng, Jiannan, Guo, Yan, Tai, Wanbo, Wang, Yufei, Du, Lanying, Zhao, Guangyu, Zhou, Yusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109928/
https://www.ncbi.nlm.nih.gov/pubmed/27312105
http://dx.doi.org/10.1016/j.antiviral.2016.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109928/
https://www.ncbi.nlm.nih.gov/pubmed/27312105
http://dx.doi.org/10.1016/j.antiviral.2016.06.003

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