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Single-cell imaging of normal and malignant cell engraftment into optically clear prkdc-null SCID zebrafish

Cell transplantation into immunodeficient mice has revolutionized our understanding of regeneration, stem cell self-renewal, and cancer; yet models for direct imaging of engrafted cells has been limited. Here, we characterize zebrafish with mutations in recombination activating gene 2 (rag2), DNA-de...

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Detalles Bibliográficos
Autores principales: Moore, John C., Tang, Qin, Yordán, Nora Torres, Moore, Finola E., Garcia, Elaine G., Lobbardi, Riadh, Ramakrishnan, Ashwin, Marvin, Dieuwke L., Anselmo, Anthony, Sadreyev, Ruslan I., Langenau, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110017/
https://www.ncbi.nlm.nih.gov/pubmed/27810924
http://dx.doi.org/10.1084/jem.20160378