High-dimensional single-cell analysis reveals the immune signature of narcolepsy

Narcolepsy type 1 is a devastating neurological sleep disorder resulting from the destruction of orexin-producing neurons in the central nervous system (CNS). Despite its striking association with the HLA-DQB1*06:02 allele, the autoimmune etiology of narcolepsy has remained largely hypothetical. Her...

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Detalles Bibliográficos
Autores principales: Hartmann, Felix J., Bernard-Valnet, Raphaël, Quériault, Clémence, Mrdjen, Dunja, Weber, Lukas M., Galli, Edoardo, Krieg, Carsten, Robinson, Mark D., Nguyen, Xuan-Hung, Dauvilliers, Yves, Liblau, Roland S., Becher, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110028/
https://www.ncbi.nlm.nih.gov/pubmed/27821550
http://dx.doi.org/10.1084/jem.20160897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110028/
https://www.ncbi.nlm.nih.gov/pubmed/27821550
http://dx.doi.org/10.1084/jem.20160897

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