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Functional expression and evaluation of heterologous phosphoketolases in Saccharomyces cerevisiae

Phosphoketolases catalyze an energy- and redox-independent cleavage of certain sugar phosphates. Hereby, the two-carbon (C2) compound acetyl-phosphate is formed, which enzymatically can be converted into acetyl-CoA—a key precursor in central carbon metabolism. Saccharomyces cerevisiae does not demon...

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Detalles Bibliográficos
Autores principales: Bergman, Alexandra, Siewers, Verena, Nielsen, Jens, Chen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110461/
https://www.ncbi.nlm.nih.gov/pubmed/27848233
http://dx.doi.org/10.1186/s13568-016-0290-0