Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of β-Catenin Signaling()

Aberrant activation of Wnt/β-catenin signaling plays a key role in the onset and development of hepatocellular carcinomas (HCC), with about half of them acquiring mutations in either CTNNB1 or AXIN1. However, it remains unclear whether these mutations impose sufficient β-catenin signaling or require...

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Detalles Bibliográficos
Autores principales: Wang, Wenhui, Xu, Lei, Liu, Pengyu, Jairam, Kiran, Yin, Yuebang, Chen, Kan, Sprengers, Dave, Peppelenbosch, Maikel P., Pan, Qiuwei, Smits, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110474/
https://www.ncbi.nlm.nih.gov/pubmed/27851986
http://dx.doi.org/10.1016/j.neo.2016.10.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110474/
https://www.ncbi.nlm.nih.gov/pubmed/27851986
http://dx.doi.org/10.1016/j.neo.2016.10.004

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