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Cardiac STAT3 Deficiency Impairs Contractility and Metabolic Homeostasis in Hypertension

Signal transducer and activator of transcription 3 (STAT3) protects the heart from acute ischemic stress. However, the importance of STAT3 to the heart in chronic stress, such as hypertension, is not known. To study this, we used cardiomyocyte-targeted STAT3 knockout (KO) mice and Angiotensin II (AN...

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Detalles Bibliográficos
Autores principales:	Altara, Raffaele, Harmancey, Romain, Didion, Sean P., Booz, George W., Zouein, Fouad A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110511/ https://www.ncbi.nlm.nih.gov/pubmed/27899891 http://dx.doi.org/10.3389/fphar.2016.00436

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