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Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children
UDP-glucuronosyltransferases (UGTs) are important phase II drug metabolism enzymes. The aim of this study was to explore the relationship between age and changes in mRNA expression and activity of major human hepatic UGTs, as well as to understand the potential regulatory mechanism underlying this r...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110524/ https://www.ncbi.nlm.nih.gov/pubmed/27899892 http://dx.doi.org/10.3389/fphar.2016.00437 |