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Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children

UDP-glucuronosyltransferases (UGTs) are important phase II drug metabolism enzymes. The aim of this study was to explore the relationship between age and changes in mRNA expression and activity of major human hepatic UGTs, as well as to understand the potential regulatory mechanism underlying this r...

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Detalles Bibliográficos
Autores principales:	Neumann, Elizabeth, Mehboob, Huma, Ramírez, Jacqueline, Mirkov, Snezana, Zhang, Min, Liu, Wanqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110524/ https://www.ncbi.nlm.nih.gov/pubmed/27899892 http://dx.doi.org/10.3389/fphar.2016.00437

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