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Disrupted autophagy undermines skeletal muscle adaptation and integrity

This review assesses the importance of proteostasis in skeletal muscle maintenance with a specific emphasis on autophagy. Skeletal muscle appears to be particularly vulnerable to genetic defects in basal and induced autophagy, indicating that autophagy is co-substantial to skeletal muscle maintenanc...

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Detalles Bibliográficos
Autores principales: Jokl, Elliot J., Blanco, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110612/
https://www.ncbi.nlm.nih.gov/pubmed/27484057
http://dx.doi.org/10.1007/s00335-016-9659-2