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Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue Glt(Tk)

Glutamate transporters catalyse the thermodynamically unfavourable transport of anionic amino acids across the cell membrane by coupling it to the downhill transport of cations. This coupling mechanism is still poorly understood, in part because the available crystal structures of these transporters...

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Detalles Bibliográficos
Autores principales: Guskov, Albert, Jensen, Sonja, Faustino, Ignacio, Marrink, Siewert J., Slotboom, Dirk Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110648/
https://www.ncbi.nlm.nih.gov/pubmed/27830699
http://dx.doi.org/10.1038/ncomms13420