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Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue Glt(Tk)
Glutamate transporters catalyse the thermodynamically unfavourable transport of anionic amino acids across the cell membrane by coupling it to the downhill transport of cations. This coupling mechanism is still poorly understood, in part because the available crystal structures of these transporters...
Autores principales: | Guskov, Albert, Jensen, Sonja, Faustino, Ignacio, Marrink, Siewert J., Slotboom, Dirk Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110648/ https://www.ncbi.nlm.nih.gov/pubmed/27830699 http://dx.doi.org/10.1038/ncomms13420 |
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