ALDH2 Inhibition Potentiates High Glucose Stress-Induced Injury in Cultured Cardiomyocytes

Aldehyde dehydrogenase (ALDH) gene superfamily consists of 19 isozymes. They are present in various organs and involved in metabolizing aldehydes that are biologically generated. For instance, ALDH2, a cardiac mitochondrial ALDH isozyme, is known to detoxify 4-hydroxy-2-nonenal, a reactive aldehyde...

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Detalles Bibliográficos
Autores principales: Pan, Guodong, Deshpande, Mandar, Thandavarayan, Rajarajan A., Palaniyandi, Suresh Selvaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110883/
https://www.ncbi.nlm.nih.gov/pubmed/27882330
http://dx.doi.org/10.1155/2016/1390861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110883/
https://www.ncbi.nlm.nih.gov/pubmed/27882330
http://dx.doi.org/10.1155/2016/1390861

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