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Forskolin Inhibits Lipopolysaccharide-Induced Modulation of MCP-1 and GPR120 in 3T3-L1 Adipocytes through an Inhibition of NFκB

In an obese state, Toll-like receptor-4 (TLR-4) upregulates proinflammatory adipokines secretion including monocyte chemotactic protein-1 (MCP-1) in adipose tissue. In contrast, G-protein coupled receptor 120 (GPR120) mediates antiobesity effects. The aim of this study was to determine the signaling...

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Detalles Bibliográficos
Autores principales: Chiadak, Jeanne Durendale, Arsenijevic, Tatjana, Verstrepen, Kevin, Gregoire, Françoise, Bolaky, Nargis, Delforge, Valérie, Flamand, Véronique, Perret, Jason, Delporte, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110889/
https://www.ncbi.nlm.nih.gov/pubmed/27881903
http://dx.doi.org/10.1155/2016/1431789