Cargando…

Forskolin Inhibits Lipopolysaccharide-Induced Modulation of MCP-1 and GPR120 in 3T3-L1 Adipocytes through an Inhibition of NFκB

In an obese state, Toll-like receptor-4 (TLR-4) upregulates proinflammatory adipokines secretion including monocyte chemotactic protein-1 (MCP-1) in adipose tissue. In contrast, G-protein coupled receptor 120 (GPR120) mediates antiobesity effects. The aim of this study was to determine the signaling...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chiadak, Jeanne Durendale, Arsenijevic, Tatjana, Verstrepen, Kevin, Gregoire, Françoise, Bolaky, Nargis, Delforge, Valérie, Flamand, Véronique, Perret, Jason, Delporte, Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110889/ https://www.ncbi.nlm.nih.gov/pubmed/27881903 http://dx.doi.org/10.1155/2016/1431789

Ejemplares similares

Involvement of JNK/NFκB Signaling Pathways in the Lipopolysaccharide-Induced Modulation of Aquaglyceroporin Expression in 3T3-L1 Cells Differentiated into Adipocytes
por: Chiadak, Jeanne Durendale, et al.
Publicado: (2016)

Lipopolysaccharide Modifies Glycerol Permeability and Metabolism in 3T3-L1 Adipocytes
por: Chiadak, Jeanne Durendale, et al.
Publicado: (2017)

Pituitary Adenylate Cyclase Activating Peptide (PACAP) Participates in Adipogenesis by Activating ERK Signaling Pathway
por: Arsenijevic, Tatjana, et al.
Publicado: (2013)

Murine 3T3-L1 Adipocyte Cell Differentiation Model: Validated Reference Genes for qPCR Gene Expression Analysis
por: Arsenijevic, Tatjana, et al.
Publicado: (2012)

Pilot study of risk factors associated with cardiovascular disease in northern and southern Cameroonians
por: Chiadak, Jeanne Durendale, et al.
Publicado: (2017)

Involvement of TonEBP/NFAT5 in osmoadaptative response of human retinal pigmented epithelial cells to hyperosmolar stress
por: Libert, Sarah, et al.
Publicado: (2016)

The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes
por: Quesada-López, Tania, et al.
Publicado: (2016)

The GPR120 Agonist TUG-891 Inhibits the Motility and Phagocytosis of Mouse Alveolar Macrophages
por: Su, Xing-Li, et al.
Publicado: (2020)

Aquaporin-1 Expression in Proliferative Vitreoretinopathy and in Epiretinal Membranes
por: Motulsky, Elie, et al.
Publicado: (2014)

GPR120 modulates epileptic seizure and neuroinflammation mediated by NLRP3 inflammasome
por: Qin, Zhangjin, et al.
Publicado: (2022)

Grifolic acid induces GH3 adenoma cell death by inhibiting ATP production through a GPR120-independent mechanism
por: Zhao, Yufeng, et al.
Publicado: (2018)

Regulation of Energy Homeostasis via GPR120
por: Ichimura, Atsuhiko, et al.
Publicado: (2014)

Medium-chain triglycerides inhibit long-chain triglyceride-induced GIP secretion through GPR120-dependent inhibition of CCK
por: Murata, Yuki, et al.
Publicado: (2021)

Effect of Forskolin on Body Weight, Glucose Metabolism and Adipocyte Size of Diet-Induced Obesity in Mice
por: Chen, Jing-Yi, et al.
Publicado: (2021)

Eicosapentaenoic acid shows anti-inflammatory effect via GPR120 in 3T3-L1 adipocytes and attenuates adipose tissue inflammation in diet-induced obese mice
por: Yamada, Hodaka, et al.
Publicado: (2017)

Hyperosmotic stress induces cell cycle arrest in retinal pigmented epithelial cells
por: Arsenijevic, T, et al.
Publicado: (2013)

Mining microarray datasets in nutrition: expression of the GPR120 (n-3 fatty acid receptor/sensor) gene is down-regulated in human adipocytes by macrophage secretions
por: Trayhurn, Paul, et al.
Publicado: (2012)

DHA/AA alleviates LPS-induced Kupffer cells pyroptosis via GPR120 interaction with NLRP3 to inhibit inflammasome complexes assembly
por: Fan, Guoqiang, et al.
Publicado: (2021)

Docosahexaenoic acid inhibits TNF-α-induced osteoclast formation and orthodontic tooth movement through GPR120
por: Ma, Jinghan, et al.
Publicado: (2023)

FFA4/GPR120: Pharmacology and Therapeutic Opportunities
por: Milligan, Graeme, et al.
Publicado: (2017)

GPR120 is an important inflammatory regulator in the development of osteoarthritis
por: Chen, Yuanfeng, et al.
Publicado: (2018)

Progress in heterologous biosynthesis of forskolin
por: Ju, Haiyan, et al.
Publicado: (2021)

GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure
por: Yu, Hongshuang, et al.
Publicado: (2021)

Effects of LPS and dietary free fatty acids on MCP-1 in 3T3-L1 adipocytes and macrophages in vitro
por: Cullberg, K B, et al.
Publicado: (2014)

Forskolin Induces Endocrine Disturbance in Human JEG-3 Placental Cells
por: Rat, Patrice, et al.
Publicado: (2022)

Inhibition by brimonidine of forskolin-induced nitric oxide synthase expression in human ciliary bodies in vitro
por: Wu, Renyi, et al.
Publicado: (2007)

Potential roles of GPR120 and its agonists in the management of diabetes
por: Zhang, Dan, et al.
Publicado: (2014)

GPR120 promotes neutrophil control of intestinal bacterial infection
por: Zhou, Zheng, et al.
Publicado: (2023)

Identification of Crocetin as a Dual Agonist of GPR40 and GPR120 Responsible for the Antidiabetic Effect of Saffron
por: Zhao, Xiaodi, et al.
Publicado: (2023)

Identification and Semi-Synthesis of 3-O-Protocatechuoylceanothic Acid, a Novel and Natural GPR120 Agonist †
por: Lim, Changjin, et al.
Publicado: (2019)

Docosahexaenoic Acid Inhibits Inflammation-Induced Osteoclast Formation and Bone Resorption in vivo Through GPR120 by Inhibiting TNF-α Production in Macrophages and Directly Inhibiting Osteoclast Formation
por: Kishikawa, Akiko, et al.
Publicado: (2019)

Central Agonism of GPR120 Acutely Inhibits Food Intake and Food Reward and Chronically Suppresses Anxiety-Like Behavior in Mice
por: Auguste, Stéphanie, et al.
Publicado: (2016)

Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation
por: Dragano, Nathalia R. V., et al.
Publicado: (2017)

Forskolin inhibits and reverses the effects of brefeldin A on Golgi morphology by a cAMP-independent mechanism
Publicado: (1991)

The Role of GPR120 Receptor in Essential Fatty Acids Metabolism in Schizophrenia
por: Rog, Joanna, et al.
Publicado: (2020)

Effect of Gambisan on the Inhibition of Adipogenesis in 3T3-L1 Adipocytes
por: Kang, Jung Won, et al.
Publicado: (2013)

Forskolin Protected against Streptozotocin-Induced Diabetic Cardiomyopathy via Inhibition of Oxidative Stress and Cardiac Fibrosis in Mice
por: Zhang, Xu, et al.
Publicado: (2021)

Forskolin attenuates retinal inflammation in diabetic mice
por: You, Zhi-Peng, et al.
Publicado: (2018)

Activation of the omega-3 fatty acid receptor GPR120 mediates anti-inflammatory actions in immortalized hypothalamic neurons
por: Wellhauser, Leigh, et al.
Publicado: (2014)

FFAR4 (GPR120) Signaling Is Not Required for Anti-Inflammatory and Insulin-Sensitizing Effects of Omega-3 Fatty Acids
por: Pærregaard, Simone Isling, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_b83vpgaoe6u2u8mrc7d5k33953