Retention of acetylcarnitine in chronic kidney disease causes insulin resistance in skeletal muscle

Insulin resistance occurs frequently in patients with chronic kidney disease. However, the mechanisms of insulin resistance associated with chronic kidney disease are unclear. It is known that an increase in the mitochondrial acetyl-CoA (AcCoA)/CoA ratio causes insulin resistance in skeletal muscle,...

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Detalles Bibliográficos
Autores principales: Miyamoto, Yasunori, Miyazaki, Teruo, Honda, Akira, Shimohata, Homare, Hirayama, Kouichi, Kobayashi, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110933/
https://www.ncbi.nlm.nih.gov/pubmed/27895387
http://dx.doi.org/10.3164/jcbn.15-146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110933/
https://www.ncbi.nlm.nih.gov/pubmed/27895387
http://dx.doi.org/10.3164/jcbn.15-146

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