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Exendin-4 induces extracellular-superoxide dismutase through histone H3 acetylation in human retinal endothelial cells

Extracellular-superoxide dismutase (genetic name SOD3) is a secreted anti-oxidative enzyme, and its presence in vascular walls may play an important role in protecting the vascular system against oxidative stress. Oxidative stress has been implicated in the pathogenesis of diabetic retinopathy; ther...

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Detalles Bibliográficos
Autores principales: Yasuda, Hiroyuki, Ohashi, Atsuko, Nishida, Shohei, Kamiya, Tetsuro, Suwa, Tetsuya, Hara, Hirokazu, Takeda, Jun, Itoh, Yoshinori, Adachi, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110938/
https://www.ncbi.nlm.nih.gov/pubmed/27895384
http://dx.doi.org/10.3164/jcbn.16-26