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Identification of Hot Spots in Protein Structures Using Gaussian Network Model and Gaussian Naive Bayes

Residue fluctuations in protein structures have been shown to be highly associated with various protein functions. Gaussian network model (GNM), a simple representative coarse-grained model, was widely adopted to reveal function-related protein dynamics. We directly utilized the high frequency modes...

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Detalles Bibliográficos
Autores principales: Zhang, Hua, Jiang, Tao, Shan, Guogen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110947/
https://www.ncbi.nlm.nih.gov/pubmed/27882325
http://dx.doi.org/10.1155/2016/4354901