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How Useful Are Monogenic Rodent Models for the Study of Human Non-Alcoholic Fatty Liver Disease?

Improving understanding of the genetic basis of human non-alcoholic fatty liver disease (NAFLD) has the potential to facilitate risk stratification of affected patients, permit personalized treatment, and inform development of new therapeutic strategies. Animal models have been widely used to interr...

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Detalles Bibliográficos
Autores principales: Mann, Jake P., Semple, Robert K., Armstrong, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110950/
https://www.ncbi.nlm.nih.gov/pubmed/27899914
http://dx.doi.org/10.3389/fendo.2016.00145