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The disruption of GDP-fucose de novo biosynthesis suggests the presence of a novel fucose-containing glycoconjugate in Plasmodium asexual blood stages

Glycosylation is an important posttranslational protein modification in all eukaryotes. Besides glycosylphosphatidylinositol (GPI) anchors and N-glycosylation, O-fucosylation has been recently reported in key sporozoite proteins of the malaria parasite. Previous analyses showed the presence of GDP-f...

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Detalles Bibliográficos
Autores principales: Sanz, Sílvia, López-Gutiérrez, Borja, Bandini, Giulia, Damerow, Sebastian, Absalon, Sabrina, Dinglasan, Rhoel R., Samuelson, John, Izquierdo, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110956/
https://www.ncbi.nlm.nih.gov/pubmed/27849032
http://dx.doi.org/10.1038/srep37230