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The disruption of GDP-fucose de novo biosynthesis suggests the presence of a novel fucose-containing glycoconjugate in Plasmodium asexual blood stages
Glycosylation is an important posttranslational protein modification in all eukaryotes. Besides glycosylphosphatidylinositol (GPI) anchors and N-glycosylation, O-fucosylation has been recently reported in key sporozoite proteins of the malaria parasite. Previous analyses showed the presence of GDP-f...
Autores principales: | Sanz, Sílvia, López-Gutiérrez, Borja, Bandini, Giulia, Damerow, Sebastian, Absalon, Sabrina, Dinglasan, Rhoel R., Samuelson, John, Izquierdo, Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110956/ https://www.ncbi.nlm.nih.gov/pubmed/27849032 http://dx.doi.org/10.1038/srep37230 |
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