Deletion of Neurotrophin Signaling through the Glucocorticoid Receptor Pathway Causes Tau Neuropathology

Glucocorticoid resistance is a risk factor for Alzheimer’s disease (AD). Molecular and cellular mechanisms of glucocorticoid resistance in the brain have remained unknown and are potential therapeutic targets. Phosphorylation of glucocorticoid receptors (GR) by brain-derived neurotrophic factor (BDN...

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Detalles Bibliográficos
Autores principales: Arango-Lievano, Margarita, Peguet, Camille, Catteau, Matthias, Parmentier, Marie-Laure, Wu, Synphen, Chao, Moses V, Ginsberg, Stephen D., Jeanneteau, Freddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110980/
https://www.ncbi.nlm.nih.gov/pubmed/27849045
http://dx.doi.org/10.1038/srep37231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110980/
https://www.ncbi.nlm.nih.gov/pubmed/27849045
http://dx.doi.org/10.1038/srep37231

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