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Deletion of Neurotrophin Signaling through the Glucocorticoid Receptor Pathway Causes Tau Neuropathology
Glucocorticoid resistance is a risk factor for Alzheimer’s disease (AD). Molecular and cellular mechanisms of glucocorticoid resistance in the brain have remained unknown and are potential therapeutic targets. Phosphorylation of glucocorticoid receptors (GR) by brain-derived neurotrophic factor (BDN...
Autores principales: | Arango-Lievano, Margarita, Peguet, Camille, Catteau, Matthias, Parmentier, Marie-Laure, Wu, Synphen, Chao, Moses V, Ginsberg, Stephen D., Jeanneteau, Freddy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110980/ https://www.ncbi.nlm.nih.gov/pubmed/27849045 http://dx.doi.org/10.1038/srep37231 |
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