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Computational model of a positive BDNF feedback loop in hippocampal neurons following inhibitory avoidance training

Inhibitory avoidance (IA) training in rodents initiates a molecular cascade within hippocampal neurons. This cascade contributes to the transition of short- to long-term memory (i.e., consolidation). Here, a differential equation-based model was developed to describe a positive feedback loop within...

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Detalles Bibliográficos
Autores principales: Zhang, Yili, Smolen, Paul, Alberini, Cristina M., Baxter, Douglas A., Byrne, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110990/
https://www.ncbi.nlm.nih.gov/pubmed/27918277
http://dx.doi.org/10.1101/lm.042044.116