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Replication fork instability and the consequences of fork collisions from rereplication

Replication forks encounter obstacles that must be repaired or bypassed to complete chromosome duplication before cell division. Proteomic analysis of replication forks suggests that the checkpoint and repair machinery travels with unperturbed forks, implying that they are poised to respond to stall...

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Detalles Bibliográficos
Autores principales: Alexander, Jessica L., Orr-Weaver, Terry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110991/
https://www.ncbi.nlm.nih.gov/pubmed/27898391
http://dx.doi.org/10.1101/gad.288142.116