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Analysis of intrapatient heterogeneity uncovers the microevolution of Middle East respiratory syndrome coronavirus

Genome sequence analysis of Middle East respiratory syndrome coronavirus (MERS-CoV) variants from patient specimens has revealed the evolutionary dynamics and mechanisms of pathogenesis of the virus. However, most studies have analyzed the consensus sequences of MERS-CoVs, precluding an investigatio...

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Detalles Bibliográficos
Autores principales: Park, Donghyun, Huh, Hee Jae, Kim, Yeon Jeong, Son, Dae-Soon, Jeon, Hyo-Jeong, Im, Eu-Hyun, Kim, Jong-Won, Lee, Nam Yong, Kang, Eun-Suk, Kang, Cheol In, Chung, Doo Ryeon, Ahn, Jin-Hyun, Peck, Kyong Ran, Choi, Sun Shim, Kim, Yae-Jean, Ki, Chang-Seok, Park, Woong-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111008/
https://www.ncbi.nlm.nih.gov/pubmed/27900364
http://dx.doi.org/10.1101/mcs.a001214