Two PTP receptors mediate CSPG inhibition by convergent and divergent signaling pathways in neurons

Receptor protein tyrosine phosphatase σ (PTPσ) and its subfamily member LAR act as transmembrane receptors that mediate growth inhibition of chondroitin sulfate proteoglycans (CSPGs). Inhibition of either receptor increases axon growth into and beyond scar tissues after CNS injury. However, it is un...

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Detalles Bibliográficos
Autores principales: Ohtake, Yosuke, Wong, Daniella, Abdul-Muneer, P. M., Selzer, Michael E., Li, Shuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111048/
https://www.ncbi.nlm.nih.gov/pubmed/27849007
http://dx.doi.org/10.1038/srep37152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111048/
https://www.ncbi.nlm.nih.gov/pubmed/27849007
http://dx.doi.org/10.1038/srep37152

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