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Two PTP receptors mediate CSPG inhibition by convergent and divergent signaling pathways in neurons
Receptor protein tyrosine phosphatase σ (PTPσ) and its subfamily member LAR act as transmembrane receptors that mediate growth inhibition of chondroitin sulfate proteoglycans (CSPGs). Inhibition of either receptor increases axon growth into and beyond scar tissues after CNS injury. However, it is un...
Autores principales: | Ohtake, Yosuke, Wong, Daniella, Abdul-Muneer, P. M., Selzer, Michael E., Li, Shuxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111048/ https://www.ncbi.nlm.nih.gov/pubmed/27849007 http://dx.doi.org/10.1038/srep37152 |
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