Cargando…

Androgen receptor (AR) signaling promotes RCC progression via increased endothelial cell proliferation and recruitment by modulating AKT → NF-κB → CXCL5 signaling

Androgen receptor (AR) signaling may promote renal cell carcinoma (RCC) progression via altered HIF-2α/VEGF signaling. However, it remains unclear whether AR signaling also promotes RCC progression by recruiting vascular endothelial cells (ECs), key players in the development of blood vessels. In ou...

Descripción completa

Detalles Bibliográficos
Autores principales: Guan, Zhenfeng, Li, Chong, Fan, Jinhai, He, Dalin, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111066/
https://www.ncbi.nlm.nih.gov/pubmed/27848972
http://dx.doi.org/10.1038/srep37085