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Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation

Proteins of the transforming-growth-factor-β (TGF-β)-superfamily have a remarkable ability to induce cartilage and bone and the crosstalk of TGF-β - and BMP-signalling pathways appears crucial during chondrocyte development. Aim was to assess the regulation of TGF-β-superfamily members and of Smad2/...

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Detalles Bibliográficos
Autores principales: Dexheimer, Verena, Gabler, Jessica, Bomans, Katharina, Sims, Tanja, Omlor, Georg, Richter, Wiltrud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111074/
https://www.ncbi.nlm.nih.gov/pubmed/27848974
http://dx.doi.org/10.1038/srep36655