Irigenin, a novel lead from Western Himalayan chemiome inhibits Fibronectin-Extra Domain A induced metastasis in Lung cancer cells

Several lines of evidence indicate that Fibronectin Extra Domain A (EDA) promotes metastatic capacity of tumor cells by engaging cell surface α9β1 integrins. This interaction mediated by the C-C loop of EDA activates pro-oncogenic signaling pathways leading to epithelial to mesenchymal transition (E...

Descripción completa

Detalles Bibliográficos
Autores principales: Amin, Asif, Chikan, Naveed Anjum, Mokhdomi, Taseem A., Bukhari, Shoiab, Koul, Aabid M., Shah, Basit Amin, Gharemirshamlu, Fatemeh Rahimi, Wafai, Asrar H., Qadri, Ayub, Qadri, Raies A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111083/
https://www.ncbi.nlm.nih.gov/pubmed/27849000
http://dx.doi.org/10.1038/srep37151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111083/
https://www.ncbi.nlm.nih.gov/pubmed/27849000
http://dx.doi.org/10.1038/srep37151

Ejemplares similares