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Irigenin, a novel lead from Western Himalayan chemiome inhibits Fibronectin-Extra Domain A induced metastasis in Lung cancer cells

Several lines of evidence indicate that Fibronectin Extra Domain A (EDA) promotes metastatic capacity of tumor cells by engaging cell surface α9β1 integrins. This interaction mediated by the C-C loop of EDA activates pro-oncogenic signaling pathways leading to epithelial to mesenchymal transition (E...

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Detalles Bibliográficos
Autores principales:	Amin, Asif, Chikan, Naveed Anjum, Mokhdomi, Taseem A., Bukhari, Shoiab, Koul, Aabid M., Shah, Basit Amin, Gharemirshamlu, Fatemeh Rahimi, Wafai, Asrar H., Qadri, Ayub, Qadri, Raies A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111083/ https://www.ncbi.nlm.nih.gov/pubmed/27849000 http://dx.doi.org/10.1038/srep37151

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