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The host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infection

Patients with P. aeruginosa airways infection show markedly variable clinical phenotypes likely influenced by genetic backgrounds. Here, we investigated the cellular events involved in resistance and susceptibility to P. aeruginosa chronic infection using genetically distinct inbred mouse strains. A...

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Detalles Bibliográficos
Autores principales: Spagnuolo, Lorenza, Simone, Maura De, Lorè, Nicola Ivan, Fino, Ida De, Basso, Veronica, Mondino, Anna, Cigana, Cristina, Bragonzi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111113/
https://www.ncbi.nlm.nih.gov/pubmed/27848994
http://dx.doi.org/10.1038/srep36924