Inhibition of connexin 43 prevents trauma-induced heterotopic ossification

Heterotopic ossification (HO) can result from traumatic injury, surgery or genetic diseases. Here, we demonstrate that overexpression of connexin 43 (Cx43) is critical for the development and recurrence of traumatic HO in patients. Inhibition of Cx43 by shRNA substantially suppressed the osteogenic...

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Detalles Bibliográficos
Autores principales: Tu, Bing, Liu, Shen, Liu, Guangwang, Li, Zhiwei, Sun, Yangbai, Fan, Cunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111117/
https://www.ncbi.nlm.nih.gov/pubmed/27849058
http://dx.doi.org/10.1038/srep37184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111117/
https://www.ncbi.nlm.nih.gov/pubmed/27849058
http://dx.doi.org/10.1038/srep37184

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