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Inhibition of connexin 43 prevents trauma-induced heterotopic ossification
Heterotopic ossification (HO) can result from traumatic injury, surgery or genetic diseases. Here, we demonstrate that overexpression of connexin 43 (Cx43) is critical for the development and recurrence of traumatic HO in patients. Inhibition of Cx43 by shRNA substantially suppressed the osteogenic...
Autores principales: | Tu, Bing, Liu, Shen, Liu, Guangwang, Li, Zhiwei, Sun, Yangbai, Fan, Cunyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111117/ https://www.ncbi.nlm.nih.gov/pubmed/27849058 http://dx.doi.org/10.1038/srep37184 |
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