A novel ENU-induced ankyrin-1 mutation impairs parasite invasion and increases erythrocyte clearance during malaria infection in mice

Genetic defects in various red blood cell (RBC) cytoskeletal proteins have been long associated with changes in susceptibility towards malaria infection. In particular, while ankyrin (Ank-1) mutations account for approximately 50% of hereditary spherocytosis (HS) cases, an association with malaria i...

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Detalles Bibliográficos
Autores principales: Huang, Hong Ming, Bauer, Denis C., Lelliott, Patrick M., Greth, Andreas, McMorran, Brendan J., Foote, Simon J., Burgio, Gaetan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111128/
https://www.ncbi.nlm.nih.gov/pubmed/27848995
http://dx.doi.org/10.1038/srep37197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111128/
https://www.ncbi.nlm.nih.gov/pubmed/27848995
http://dx.doi.org/10.1038/srep37197

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