Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis

Cancer cells of epithelial and mesenchymal phenotypes exhibit different sensitivities to apoptosis stimuli, but the mechanisms underlying this phenomenon remain partly understood. We constructed a novel recombinant adenovirus expressing Ad12 E1A (Ad-E1A12) that can strongly induce apoptosis. Ad-E1A1...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yunfei, Li, Dawei, Luo, Jian, Tian, Guimei, Zhao, Lisa Y., Liao, Daiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111159/
https://www.ncbi.nlm.nih.gov/pubmed/27849011
http://dx.doi.org/10.1038/srep37213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111159/
https://www.ncbi.nlm.nih.gov/pubmed/27849011
http://dx.doi.org/10.1038/srep37213

Ejemplares similares