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Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis

Cancer cells of epithelial and mesenchymal phenotypes exhibit different sensitivities to apoptosis stimuli, but the mechanisms underlying this phenomenon remain partly understood. We constructed a novel recombinant adenovirus expressing Ad12 E1A (Ad-E1A12) that can strongly induce apoptosis. Ad-E1A1...

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Detalles Bibliográficos
Autores principales:	Wang, Yunfei, Li, Dawei, Luo, Jian, Tian, Guimei, Zhao, Lisa Y., Liao, Daiqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111159/ https://www.ncbi.nlm.nih.gov/pubmed/27849011 http://dx.doi.org/10.1038/srep37213

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