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Natural product HTP screening for antibacterial (E.coli 0157:H7) and anti-inflammatory agents in (LPS from E. coli O111:B4) activated macrophages and microglial cells; focus on sepsis

BACKGROUND: Acute systemic inflammatory response syndrome arising from infection can lead to multiple organ failure and death, with greater susceptibility occurring in immunocompromised individuals. Moreover, sub-acute chronic inflammation is a contributor to the pathology of diverse degenerative di...

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Detalles Bibliográficos
Autores principales: Mazzio, Elizabeth A., Li, Nan, Bauer, David, Mendonca, Patricia, Taka, Equar, Darb, Mohammed, Thomas, Leeshawn, Williams, Henry, Soliman, Karam F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111180/
https://www.ncbi.nlm.nih.gov/pubmed/27846826
http://dx.doi.org/10.1186/s12906-016-1429-x