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Upregulation of miR-501-5p activates the wnt/β-catenin signaling pathway and enhances stem cell-like phenotype in gastric cancer

BACKGROUND: miRNAs are critical post-transcriptional regulators of gene expression and key mediators of tumourigenesis. miR-501-5p is newly identified to be involved in the tumor progression, but its biological role and mechanism remain largely unknown. This study is aimed to study the role of miR-5...

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Detalles Bibliográficos
Autores principales: Fan, Dongmei, Ren, Baoqi, Yang, Xiaojun, Liu, Jia, Zhang, Zhengzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111270/
https://www.ncbi.nlm.nih.gov/pubmed/27846906
http://dx.doi.org/10.1186/s13046-016-0432-x