CRISPR interference (CRISPRi) for gene regulation and succinate production in cyanobacterium S. elongatus PCC 7942

BACKGROUND: Cyanobacterium Synechococcus elongatus PCC 7942 holds promise for biochemical conversion, but gene deletion in PCC 7942 is time-consuming and may be lethal to cells. CRISPR interference (CRISPRi) is an emerging technology that exploits the catalytically inactive Cas9 (dCas9) and single g...

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Detalles Bibliográficos
Autores principales: Huang, Chun-Hung, Shen, Claire R., Li, Hung, Sung, Li-Yu, Wu, Meng-Ying, Hu, Yu-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111286/
https://www.ncbi.nlm.nih.gov/pubmed/27846887
http://dx.doi.org/10.1186/s12934-016-0595-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111286/
https://www.ncbi.nlm.nih.gov/pubmed/27846887
http://dx.doi.org/10.1186/s12934-016-0595-3

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