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CRISPR interference (CRISPRi) for gene regulation and succinate production in cyanobacterium S. elongatus PCC 7942

BACKGROUND: Cyanobacterium Synechococcus elongatus PCC 7942 holds promise for biochemical conversion, but gene deletion in PCC 7942 is time-consuming and may be lethal to cells. CRISPR interference (CRISPRi) is an emerging technology that exploits the catalytically inactive Cas9 (dCas9) and single g...

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Detalles Bibliográficos
Autores principales:	Huang, Chun-Hung, Shen, Claire R., Li, Hung, Sung, Li-Yu, Wu, Meng-Ying, Hu, Yu-Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111286/ https://www.ncbi.nlm.nih.gov/pubmed/27846887 http://dx.doi.org/10.1186/s12934-016-0595-3

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