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Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A
BACKGROUND: The gene PPARGC1A, in particular the Gly482Ser variant (rs8192678), had been proposed to be subject to natural selection, particularly in recent progenitors of extant Polynesian populations. Reasons include high levels of population differentiation and increased frequencies of the derive...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111290/ https://www.ncbi.nlm.nih.gov/pubmed/27846814 http://dx.doi.org/10.1186/s12881-016-0341-z |