Cargando…
Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A
BACKGROUND: The gene PPARGC1A, in particular the Gly482Ser variant (rs8192678), had been proposed to be subject to natural selection, particularly in recent progenitors of extant Polynesian populations. Reasons include high levels of population differentiation and increased frequencies of the derive...
Autores principales: | Cadzow, Murray, Merriman, Tony R., Boocock, James, Dalbeth, Nicola, Stamp, Lisa K., Black, Michael A., Visscher, Peter M., Wilcox, Phillip L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111290/ https://www.ncbi.nlm.nih.gov/pubmed/27846814 http://dx.doi.org/10.1186/s12881-016-0341-z |
Ejemplares similares
-
A bioinformatics workflow for detecting signatures of selection in genomic data
por: Cadzow, Murray, et al.
Publicado: (2014) -
Performance of gout definitions for genetic epidemiological studies: analysis of UK Biobank
por: Cadzow, Murray, et al.
Publicado: (2017) -
Association of SLC2A9 genotype with phenotypic variability of serum urate in pre-menopausal women
por: Topless, Ruth K., et al.
Publicado: (2015) -
Genetic testing for misclassified monogenic diabetes in Māori and Pacific peoples in Aōtearoa New Zealand with early-onset type 2 diabetes
por: Toomata, Zanetta, et al.
Publicado: (2023) -
The PPARGC1A Is the Gene Responsible for Thrifty Metabolism Related Metabolic Diseases: A Scoping Review
por: Aisyah, Riandini, et al.
Publicado: (2022)