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The Evaluation and Comparison of Transcriptionally Targeted Noxa and Puma Killer Genes to Initiate Apoptosis Under Cancer-Specific Promoter CXCR1 in Hepatocarcinoma Gene Therapy

BACKGROUND: Cancerous cells proliferate as fast as possible without a proper surveillance system. This rapid cell division leads to enormous mutation rates, which help a tumor establish. OBJECTIVES: This study evaluated the potential of inducing apoptosis using Noxa and Puma in a hepatocarcinoma cel...

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Detalles Bibliográficos
Autores principales: Khoshtinat Nikkhoi, Shahryar, Heydarzadeh, Hedieh, Ranjbar, Saeed, Salimi, Fatemeh, Aghaeifard, Masoud, Alavian, Seyed Moayed, Reshadmanesh, Azadeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111460/
https://www.ncbi.nlm.nih.gov/pubmed/27882064
http://dx.doi.org/10.5812/hepatmon.38828