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The novel functional nucleic acid iRed effectively regulates target genes following cytoplasmic delivery by faint electric treatment

An intelligent shRNA expression device (iRed) contains the minimum essential components needed for shRNA production in cells, and could be a novel tool to regulate target genes. However, general delivery carriers consisting of cationic polymers/lipids could impede function of a newly generated shRNA...

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Detalles Bibliográficos
Autores principales: Hasan, Mahadi, Tarashima, Noriko, Fujikawa, Koki, Ohgita, Takashi, Hama, Susumu, Tanaka, Tamotsu, Saito, Hiroyuki, Minakawa, Noriaki, Kogure, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111564/
https://www.ncbi.nlm.nih.gov/pubmed/27877903
http://dx.doi.org/10.1080/14686996.2016.1221726