11β‐Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation

Muscle wasting is a common feature of inflammatory myopathies. Glucocorticoids (GCs), although effective at suppressing inflammation and inflammatory muscle loss, also cause myopathy with prolonged administration. 11β‐Hydroxysteroid dehydrogenase type 1 (11β‐HSD1) is a bidirectional GC‐activating en...

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Detalles Bibliográficos
Autores principales: Hardy, Rowan S, Doig, Craig L, Hussain, Zahrah, O'Leary, Mary, Morgan, Stuart A, Pearson, Mark J, Naylor, Amy, Jones, Simon W, Filer, Andrew, Stewart, Paul M, Buckley, Christopher D, Lavery, Gareth G, Cooper, Mark S, Raza, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111591/
https://www.ncbi.nlm.nih.gov/pubmed/27578244
http://dx.doi.org/10.1002/path.4806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111591/
https://www.ncbi.nlm.nih.gov/pubmed/27578244
http://dx.doi.org/10.1002/path.4806

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