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Single‐Molecule Fluorescence Detection of a Synthetic Heparan Sulfate Disaccharide

The first single‐molecule fluorescence detection of a structurally‐defined synthetic carbohydrate is reported: a heparan sulfate (HS) disaccharide fragment labeled with Alexa488. Single molecules have been measured whilst freely diffusing in solution and controlled encapsulation in surface‐tethered...

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Detalles Bibliográficos
Autores principales: Dalton, Charlotte E., Quinn, Steven D., Rafferty, Aidan, Morten, Michael J., Gardiner, John M., Magennis, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111599/
https://www.ncbi.nlm.nih.gov/pubmed/27538128
http://dx.doi.org/10.1002/cphc.201600750