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The relationship between glucocerebrosidase mutations and Parkinson disease

Parkinson disease (PD) is the second most common neurodegenerative disorder after Alzheimer disease, whereas Gaucher disease (GD) is the most frequent lysosomal storage disorder caused by homozygous mutations in the glucocerebrosidase (GBA1) gene. Increased risk of developing PD has been observed in...

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Detalles Bibliográficos
Autores principales: Migdalska‐Richards, Anna, Schapira, Anthony H. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111601/
https://www.ncbi.nlm.nih.gov/pubmed/26860875
http://dx.doi.org/10.1111/jnc.13385