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Identification of novel BRCA founder mutations in Middle Eastern breast cancer patients using capture and Sanger sequencing analysis

Ethnic differences of breast cancer genomics have prompted us to investigate the spectra of BRCA1 and BRCA2 mutations in different populations. The prevalence and effect of BRCA 1 and BRCA 2 mutations in Middle Eastern population is not fully explored. To characterize the prevalence of BRCA mutation...

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Detalles Bibliográficos
Autores principales: Bu, Rong, Siraj, Abdul K., Al‐Obaisi, Khadija A.S., Beg, Shaham, Al Hazmi, Mohsen, Ajarim, Dahish, Tulbah, Asma, Al‐Dayel, Fouad, Al‐Kuraya, Khawla S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111783/
https://www.ncbi.nlm.nih.gov/pubmed/27082205
http://dx.doi.org/10.1002/ijc.30143