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A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan

Animal models of thrombocytopenia are indispensable for evaluating the in vivo efficacy of hemostatic agents, cryopreserved platelets, and artificial platelets, but no large animal models are available. In this study, we generated a swine model of acute thrombocytopenia with prolonged bleeding times...

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Detalles Bibliográficos
Autores principales: Abe, Tomoyuki, Kono, Shota, Ohnuki, Takahiro, Hishikawa, Shuji, Kunita, Satoshi, Hanazono, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111837/
https://www.ncbi.nlm.nih.gov/pubmed/27333841
http://dx.doi.org/10.1538/expanim.16-0022